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For laboratory and in-vitro research use only · Not for human consumption
ResearchWater
LC-MS Mass Spec-Grade Water 1 L glass bottle
RW-LCMS-500

LC-MS Mass Spec-Grade Water

Sub-ppb metals and TOC, low VOCs, LC-MS-tested before release. The grade you want when sodium adducts and ion suppression are the difference between data and rerun.

$39.99 $79.98 / L · CofA included
Pack size
LC-MS tested per lot CofA per lot Sub-ppb metals 0.1 µm filtered

Specifications

Resistivity18.2 MΩ·cm @ 25 °C
TOC< 5 ppb
Trace metalsNa, K, Ca, Mg each < 1 ppb
Filtration0.1 µm filtered
VOCLow VOC, screened by GC-MS
QC releaseLC-MS tested prior to release; sub-ppb adduct check
ContainerClear glass bottle, PTFE-lined cap, tamper-evident closure
Lot trackingLot number printed on bottle; CofA accessible at /lab-results/
Applications

Where this SKU is used in research workflows.

LC-MS/MS mobile phase

Aqueous channel for LC-MS/MS where sodium and potassium adducts must be minimized. Sub-ppb metal levels keep MS background ions below the limit of detection.

UHPLC gradients

UHPLC pumps and sub-2-µm columns benefit from 0.1 µm filtration that protects against frit blockage and back-pressure drift.

ICP-MS sample dilution

Dilute samples and acid blanks for ICP-MS where ng/L-level metal contamination determines whether a calibration curve clears the blank threshold.

Peptide mapping & proteomics

Reconstitute tryptic digests, prepare loading buffers, and dilute proteomics samples without introducing keratin contaminants or polymer leachables.

Research use only. This product is not for human or veterinary consumption, clinical use, diagnostic procedures, or therapeutic purposes. By purchasing, you affirm you are a qualified researcher or laboratory professional aged 21 or older.
Common questions

About this product.

Why is "mass-spec-grade" different from HPLC-grade?

Mass-spec-grade specifies sub-ppb levels on Na, K, Ca, Mg, and TOC, plus a low VOC profile and per-lot LC-MS release testing. HPLC-grade meets HPLC particulate and UV-cutoff specs but does not specify sub-ppb metals, which is what causes adduct interference and ion suppression on mass spectrometers.

Does it work for negative-mode LC-MS?

Yes. The same sub-ppb metals and low-VOC profile that suppress positive-mode adducts also keep negative-mode background clean. Premix with formic acid (typical positive mode) or ammonium acetate / ammonium formate (typical negative mode) immediately before use.

Is it ICP-MS compatible?

Yes. Sub-ppb levels of Na, K, Ca, and Mg, plus 0.1 µm filtration and a clean glass + PTFE container, make this SKU suitable for ICP-MS sample dilution and standard preparation. For ultratrace work below 100 ppt, perform an instrument blank to confirm.

How do I download the Certificate of Analysis?

Visit our Lab Results portal and enter the lot number printed on the bottle. You'll receive the full CofA — including resistivity, TOC, sub-ppb metals panel, and LC-MS release trace — as a downloadable PDF.